The branch conducts interdisciplinary basic research in exobiology to understand pre-biotic chemistry, and the origin, evolution, distribution, and future of life in the Universe. We provide an interface between the external academic community and NASA programs. Our work also informs the selection, design and development of NASA life detection missions; the design and fabrication of spaceflight instruments to evaluate habitability and detect biosignatures; and the interpretation of astrobiology mission and astronomical data.
The CheMin Instrument
The Exobiology Branch is home to David Blake, the Principal Investigator for the CheMin instrument on the Mars Science Laboratory, scheduled for launch in 2011.
The CheMin instrument utilizes X-ray diffraction and flourescence to provide difinitive minerology of rock samples (both elemental analysis and crystal structure determination).
Early Habitable Environments and the Evolution of Complexity
The Exobiology Branch is home to David Des Marais, the Principal Investigator of the NASA Astrobiology Institute (NAI) Ames Team, which focuses on Early Habitable Environments and the Evolution of Complexity. The overarching goal of this scientific program is to understand the creation and distribution of early habitable environments in emerging planetary systems. The Ames Team provides a program of integrative, mission-enabled and mission-enabling research on habitability and a thematically related program of education and public outreach focused around informal education in high-impact venues. Andrew Pohorille, Tori Hoehler, and Sandy Dueck are also members of the Exobiology Branch and hold key roles as Lead Co-Investigators on the team. To learn more about the NAI Ames Team, visit their website at www.amesteam.arc.nasa.gov.
Origin of Life Research
For nearly 40 years, the Exobiology Branch at Ames has been the main center for origins of life research at NASA, and a world leader in this scientific area. Currently, the branch has the unique feature of being the only center within the NASA Astrobiology Program that has a sustained, long-term program of theoretical and computational studies on the origins of life. This research program, which contains both molecular and system-level components, is leveraged by the supercomputing facilities at Ames and by Ames’ status as the NASA lead center in information science and technology.
The image shown above is the cover art for the latest issue of the Journal of Physical Chemistry, highlighting an article by Andrew Pohorille, a Principal Investigator in the Branch, with co-authors Christopher Jarzynski and Christophe Chipot, titled “Good practices in free-energy calculations”. From the abstract: “As access to computational resources continues to increase, free-energy calculations have emerged as a powerful tool that can play a predictive role in a wide range of research areas. … In this contribution, the current best practices for carrying out free-energy calculations using free energy perturbation and nonequilibrium work methods are discussed demonstrating that, at little to no additional cost, free-energy estimates could be markedly improved and bounded by meaningful error estimates.”
Dr. Pohorille is also the recepient of this year’s H. Julian Allen Award, bestowed by NASA Ames for best research paper. Titled “Calculating free energies using average force”, the paper appeared in the Journal of Chemical Physics (co-author Eric Darve), Volume 115, Number 20, November 2001. According to the Citation Index in the Web of Science the paper has been cited 111 times as of March 2010. From the abstract: “A new, general formula that connects the derivatives of the free energy along the selected, generalized coordinates of the system with the instantaneous force acting on these coordinates is derived. The instantaneous force is defined as the force acting on the coordinate of interest so that when it is subtracted from the equations of motion the acceleration along this coordinate is zero. The formula applies to simulations in which the selected coordinates are either unconstrained or constrained to fixed values.”
The Branch is also home to Dr. Arthur Weber, a SETI Institute researcher, who works together with his wife Esther to study the pre-biotic chemistry of sugars, and how these molecules may have led to the origin of life.
The Branch is housed in Building 239 at NASA Ames Research Center. Laboratory facilities available include analytical equipment for the characterization of gas and aqueous chemistry, instruments for the detection of various biomarkers including sugars and organics, microbiology facilities including the culture of microbial mat communities, electron and RAMAN microscopes, a molecular biology suite, and informatics computational capabilities.
Code SSX Highlights
Tori Hoehler (SSX) was a keynote speaker at an international conference on scientific ocean drilling in Bremen, Germany. The conference, attended by more than 600 scientists, government officials, and funding agency representatives, served to establish science and technology priorities for the next decade of deep-ocean drilling. At the request of the conference organizers, Hoehler’s presentation […]
On 9/28 Andrew Pohorille gave an invited seminar “Origin of protein functions in cells” at the Origins Institute at McMaster University in Ontario, Canada. The Origin Institute, formed in 2004, is a main Canadian research and education center devoted to: The Origin of Space-Time The Origins of Structure in the Cosmos The Origins of Elements […]
Dr. Tori Hoehler will be featured on the next episode of the SETI Institute’s radio program, “Are We Alone?”. Contributing to an episode entitled “Slime World”, Hoehler discusses the prominent focus of astrobiology research on microorganisms (“slime”), including the the attributes that may make microbial life the most abundant form in the universe. “Are We […]
On March 7, Dr. David Des Marais gave a public lecture in Columbia, MO (University of Missouri) that received press coverage. See link below: http://www.columbiatribune.com/news/2009/mar/08/mars-lecture-captivates-crowd/ […]
A manuscript by George Cooper entitled: “Gas Chromatography-Mass Spectrometry Resolution of Sugar Acid Enantiomers on a Permethylated beta-Cyclodextrin Stationary Phase” has been accepted for publication in The Journal of Chromatograhy A. The manuscript describes the separation of laboratory standards of mirror-images (enantiomers) of individual sugar acids, e.g., glyceric, erythronic, ribonic, etc. This class of organic […]